That's where it all begins, the choices will be clearer when piston size is determined.
Then ask yourself what compression ratio do you want to run?
More compression is more HP, but you also need to control your timing curve more closely.
And decide what octane fuel you will run.
I started with a used block needing .080 custom pistons.
You will hopefully find off the shelf ones for your needs.
I run 9.5+ comp. ratio, burn 87 octane always.
Sniper FI with timing control.
When the Sniper works, it's great!
I believe the Sniper 2 is improved over mine.
Camshaft intake valve closing can help with higher static compression.
Static vs Dynamic.